Section Summary. Replication in eukaryotes starts at multiple origins of replication. The mechanism is quite similar to prokaryotes. A primer is required to initiate synthesis, which is then extended by DNA polymerase as it adds nucleotides one by one to the growing chain. Before replication can start, the DNA has to be made available as a template. Eukaryotic DNA is bound to basic proteins known as histones to form structures called nucleosomes. Histones must be removed and then replaced during the replication process, which helps to account for the lower replication rate in eukaryotes. Initiation of Eukaryotic DNA replication is similar to pc-supply.biz, replication, in Eukaryotic replication, it is initiated at a unique location on the SV40 DNA by inter activation of a virus-encoded, site-specific DNA binding protein called “pc-supply.bizn”. Prokaryotic DNA Polymerases; Fidelity of DNA Replication.
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